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Bioinformatician

Bioinformatician

Centro Nacional de Análisis GenómicoBarcelona, Província de Barcelona, España
Hace 16 días
Descripción del trabajo

Location : Office in Barcelona (Spain). Date of Publication : 15 / 07 / 2025 About Us : The Centro Nacional de Análisis Genómico (CNAG) is one of the largest Genome Sequencing Centers in Europe. The CNAG Consortium carries out large-scale projects in DNA / RNA analysis for the improvement of quality of life in collaboration with the Spanish, European and International Research Community. The Centro Nacional de Análisis Genómico (CNAG) is one of the largest Genome Sequencing Centers in Europe, with several Illumina and Oxford Nanopore Technologies sequencers, state-of-the-art single-cell equipment, and an extensive informatics infrastructure. The operation is certified ISO 9001 and accredited ISO 17025, delivering standardized, high-quality data for research and clinics. The CNAG has over 125 professionals and participates in major International Genome Initiatives and EU-funded projects. The Role We are looking for a highly motivated bioinformatician with a PhD to join the SEED-ALS Spain project, a national research initiative focused on understanding and treating Amyotrophic Lateral Sclerosis (ALS) through a multi-omics, longitudinal, and precision medicine approach. The selected candidate will be involved in the integration and analysis of genomic, transcriptomic, epigenomic, and proteomic data to identify disease mechanisms, biomarkers of progression, and therapeutic targets in ALS. The project is part of the 2024 call for grants to Personalized Precision Medicine Research Projects from the Instituto de Salud Carlos III, funded by the European Union – NextGenerationEU, under the Recovery, Transformation and Resilience Plan (Project Code PMPER24 / 00017). Key aspects of SEED-ALS : Multicenter consortium involving clinical and translational research groups across Spain Comprehensive characterization of ALS using longitudinal samples and multi-omics profiling Development of predictive models of disease progression Strong translational focus including preclinical testing platforms More about the SEED-ALS initiative : ✍️ Responsibilities : Design, develop, and maintain bioinformatics pipelines for the analysis of short-read and long-read sequencing data. Integrate genomic, transcriptomic, and epigenomic data, including DNA variants, RNA expression, splicing, and methylation profiles. Contribute to variant prioritization and patient stratification through multi-omics data interpretation. Whom would we like to hire? PhD in bioinformatics, computational biology, or related field Proficiency in NGS data processing and analysis (>

5 years) Experience in short-read and long-read WGS data analysis Experience with RNA-seq and methylation analysis Strong programming skills (e.g., R, Python) and familiarity with HPC environments Interest in neurodegenerative diseases and translational research Teamwork and communication skills in a multidisciplinary environment ✍️ Nice to have : Experience in clinical genetics The Offer Contract duration : Full-time contract within a nationally funded, high-impact project Estimated annual gross salary : Salary is commensurate with qualifications and consistent with our pay scales. Target start date : before 2026 Opportunity to work at the intersection of clinical and computational research Collaborative environment with leading ALS researchers and institutions ✅ Benefits Highly stimulating environment with state-of-the-art infrastructures, and unique Professional Career Plan and development opportunities. We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, race, religion or sexual orientation. We are committed to reconcile work and family life for our employees and are offering the opportunity to benefit from annual leave and flexible working hours. We look forward to receiving your application and discovering how you can contribute to CNAG's success! Application Procedure All applications must include : A complete CV including contact details. Contact details of two referees. All applications must be addressed to : Mireya Fernández – Anna Esteve – Deadline : Please submit your application by 30 / 09 / 2025 Interview : Shortlisted candidates will be called for an interview. See the CNAG Career site at our website :

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Bioinformatician • Barcelona, Província de Barcelona, España

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