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PROTEOMICS SPECIALIST RESEARCHER Reus - Tarragona

PROTEOMICS SPECIALIST RESEARCHER Reus - Tarragona

Eurecat - Centro TecnológicoReus, Cataluña, España
Hace 9 horas
Descripción del trabajo

Overview

The Omic Sciences Department carries out its activities using state-of-the-art infrastructures at the Centre for Omic Sciences (COS), a unique center equipped with the latest metabolomics, proteomics, transcriptomics, and genomics technologies. It offers a comprehensive range of biomarker research services across health, food, and environmental sectors, from project design support to the analysis and integration of data obtained from various omics technologies.

We are seeking an experienced and highly skilled Specialist Proteomics researcher to join our cutting-edge Proteomics Platform. The successful candidate will work closely with researchers and industry partners to advance proteomics methodologies, particularly in ultra-sensitive quantitative proteomics, post-translational modifications (PTMs), and integrative multi-omics approaches.

Responsibilities

  • Expert operation and maintenance of state-of-the-art LC-MS / MS systems.
  • Development and optimization of novel nanoLC-MS / MS workflows, including label-free quantification, targeted proteomics, and DIA (Data-Independent Acquisition) workflows.
  • In-depth proteomic analysis of complex biological samples (tissues, cell lines, biofluids), with a focus on post-translational modifications (PTMs), glycoproteomics, and interaction proteomics.
  • Implementation of advanced mass spectrometry techniques for global and targeted proteomics, including TMT-labelling and affinity-enrichment workflows.
  • Integration of proteomics data with other omics platforms (e.g., metabolomics, transcriptomics) to support interdisciplinary biological research.
  • Data processing and bioinformatics analysis using tools such as Spectronaut, MaxQuant, Proteome Discoverer, Skyline.
  • Scientific consulting and collaboration with research teams to design experiments, analyze results, and interpret biological insights.
  • Hands-on supervision of proteomics projects, ensuring high-quality data acquisition and analysis.
  • Training and mentoring of PhD students, postdoctoral researchers, and users in proteomics techniques and data analysis.
  • Scientific dissemination through participation in national and international conferences, workshops, and peer-reviewed publications.
  • Routine laboratory management, including instrument calibration, troubleshooting, and compliance with ISO9001-certified quality standards.

Requirements

Qualifications

  • PhD in Analytical Chemistry, Biochemistry, Molecular Biology, or a related field.
  • Alternatively, a minimum of 5 years of hands-on experience in mass spectrometry-based proteomics, with a strong focus on post-translational modifications (PTMs) and glycoproteomics analysis.

    • Knowledge and Experience

  • Extensive experience in nanoLC-MS / MS-based proteomics, including sample preparation, enzymatic digestion, isobaric labeling, and chromatographic optimization.
  • Strong expertise in Orbitrap mass spectrometry.
  • Proficiency in mass spectrometry data processing and bioinformatics tools (e.g., MaxQuant, Spectronaut, Proteome Discoverer).
  • Experience in quantitative proteomics workflows, including DIA, TMT, and SILAC.
  • Solid understanding of PTMs, glycoproteomics, and phosphoproteomics workflows.
  • Experience in high-throughput automated sample preparation using liquid-handling robotics.
  • Fluency in English (both written and spoken, B1 level), with proficiency in Spanish and Catalan considered an asset.
  • Ability to work independently in a multidisciplinary, international research environment.
  • Strong communication and presentation skills for effective collaboration with academic and industry partners.

    • Additional Valued Skills

  • Experience working in a core facility, industry, or research infrastructure.
  • Experience in protein structural analysis and integrative omics approaches.
  • Background in mass spectrometry imaging (MALDI-imaging) and small molecule analysis.
  • Expertise in native mass spectrometry and interaction proteomics.
  • Programming and data analysis skills (e.g., Python, R) are highly desirable.

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    Specialist Tarragona • Reus, Cataluña, España